- number of symptoms at the onset of MS.
- Time course (onset and progression).
- Onset age.
- Neurological status at 5 years after the onset of MS.
- For the most part, the course of ms remains unpredictable.
- There are certain factors that make the symptoms worse:
a. Deterioration of general health.
b. Viral or bacterial infection.
d. Pregnancy and birth giving.
e. Emotional stress of excessive fatigue.
f. Rise in body temperature (fever, hot bath or hot weather).
g. Dehydration and malnutrition.
The Diagnosis is largely clinical.
The basic criteria are:
- Evidence of multiple lesions in the CNS.
- Evidence (clinical or paraclinical) of at least two distinct episodes of neurological disturbances in an individual (age of 10-59 years).
Paraclinical evidence may include:
b. Evoked potentials: VEP,BAEP,SSEP.
c. CSF: many cases show high gamma globulin and some show elevated WBC or fragments of myelin or myelin basic protein.